2018
Eliane Ngassam; Marcel Azabji-Kenfack; Aurel T. Tankeu; Liliane Mfeukeu-Kuate; Chris-Nadège Nganou-Gnindjio; Camille Mba; Jean Claude Katte; Mesmin Y. Dehayem; Jean Claude Mbanya; Eugène Sobngwi
Heart rate variability in hyperthyroidism on sub Saharan African patients: a case–control study Article de journal
Dans: BMC Research Notes, vol. 11, iss. 1, p. 814, 2018, ISSN: 1756-0500.
Résumé | Liens | BibTeX | Étiquettes: Africa, Heart rate variability, Hyperthyroidism, Short-term
@article{Ngassam2018,
title = {Heart rate variability in hyperthyroidism on sub Saharan African patients: a case–control study},
author = {Eliane Ngassam and Marcel Azabji-Kenfack and Aurel T. Tankeu and Liliane Mfeukeu-Kuate and Chris-Nadège Nganou-Gnindjio and Camille Mba and Jean Claude Katte and Mesmin Y. Dehayem and Jean Claude Mbanya and Eugène Sobngwi},
url = {https://doi.org/10.1186/s13104-018-3922-4 https://bmcresnotes.biomedcentral.com/articles/10.1186/s13104-018-3922-4},
doi = {10.1186/s13104-018-3922-4},
issn = {1756-0500},
year = {2018},
date = {2018-01-01},
journal = {BMC Research Notes},
volume = {11},
issue = {1},
pages = {814},
publisher = {BioMed Central},
abstract = {Objective: We aimed to determine heart rate variability in freshly diagnosed untreated hyperthyroidism patients. We enrolled 10 patients (9 females) and 10 matched controls for sex and age. Each eligible patient underwent five different tests according to Ewing battery tests for cardiac autonomic dysfunction assessment. HRV was assessed during each maneuver and on 24 h using a continuous electrocardiogram with automatic estimation of SDNN, RMSSD, LF HF and HF/LH ratio. Results of tests were compared between hyperthyroidism patients and matched controls using the non-parametric test of Mann-Whitney. Results: Heart rate was significantly higher in patients with thyrotoxicosis (82.91 ± 10.99 vs 67.04 ± 6.80; 0.006) compared to their controls. On time-domain analysis, there was a trend towards reduction in SDNN (39.52 vs. 63.75; p = 0.2) as well as the RMSSD (30.44 vs 64.03; p = 0.09) in patients with hyperthyroidism. The frequency-domain analysis showed non-significant higher values for the LF (43.87 vs 38.85 ± 12.85; p = 0.8) and lower for the HF (32.54 vs 43.39; p = 0.3). Test's results were mostly impaired in hyperthyroid patients and all patients presented abnormal results for parasympathetic activity. Untreated and recently diagnosed hyperthyroidism is associated to an altered parasympathetic activity in sub Saharan African patients.},
keywords = {Africa, Heart rate variability, Hyperthyroidism, Short-term},
pubstate = {published},
tppubtype = {article}
}
Objective: We aimed to determine heart rate variability in freshly diagnosed untreated hyperthyroidism patients. We enrolled 10 patients (9 females) and 10 matched controls for sex and age. Each eligible patient underwent five different tests according to Ewing battery tests for cardiac autonomic dysfunction assessment. HRV was assessed during each maneuver and on 24 h using a continuous electrocardiogram with automatic estimation of SDNN, RMSSD, LF HF and HF/LH ratio. Results of tests were compared between hyperthyroidism patients and matched controls using the non-parametric test of Mann-Whitney. Results: Heart rate was significantly higher in patients with thyrotoxicosis (82.91 ± 10.99 vs 67.04 ± 6.80; 0.006) compared to their controls. On time-domain analysis, there was a trend towards reduction in SDNN (39.52 vs. 63.75; p = 0.2) as well as the RMSSD (30.44 vs 64.03; p = 0.09) in patients with hyperthyroidism. The frequency-domain analysis showed non-significant higher values for the LF (43.87 vs 38.85 ± 12.85; p = 0.8) and lower for the HF (32.54 vs 43.39; p = 0.3). Test's results were mostly impaired in hyperthyroid patients and all patients presented abnormal results for parasympathetic activity. Untreated and recently diagnosed hyperthyroidism is associated to an altered parasympathetic activity in sub Saharan African patients.